EPNONE 50mg is a medication used to treat heart failure and high blood pressure. It helps reduce fluid retention and relieve stress on the heart by blocking the effects of the hormone aldosterone, which improves heart performance and reduces complications.
Benefits and Uses of EPNONE 50mg
Epnone tablet belongs to a class of drugs known as selective aldosterone blockers, which inhibit the action of aldosterone — a hormone responsible for regulating blood pressure and heart function.
It is used for:
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Treating heart failure after a heart attack to prevent worsening of the condition and reduce hospital admissions.
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Managing chronic heart failure in patients with mild to moderate symptoms despite conventional therapy.
How to Use epnone tablet
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Take the medication exactly as prescribed by your doctor.
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It can be taken with or without food, with a glass of water.
Usual dosage:
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Start with 25 mg once daily, then increase to 50 mg once daily after about 4 weeks.
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The maximum dose is 50 mg per day.
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Blood potassium levels should be checked before starting treatment, and again after 1 week and 1 month, then as needed.
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For mild kidney impairment, the dose is 25 mg daily; for moderate impairment, 25 mg every other day.
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Not recommended in severe kidney or liver impairment.
Side Effects
Common side effects may include:
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High potassium levels (may cause muscle cramps, dizziness, or nausea).
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Dizziness or fainting due to low blood pressure.
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Headache or insomnia.
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Irregular heartbeat.
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Digestive issues such as nausea, vomiting, diarrhea, or constipation.
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Rash or itching.
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Fatigue or back pain.
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Elevated urea and creatinine levels, which may indicate kidney effects.
Precautions and Warnings
Consult your doctor before using Epinon if you have:
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Kidney or liver problems.
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Are taking lithium, tacrolimus, or cyclosporine.
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Are pregnant or breastfeeding.
Do not use in the following cases:
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Allergy to eplerenone or any ingredient of the product.
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High potassium levels in the blood.
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Severe kidney or liver disease.
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When taking potassium-sparing diuretics or certain antifungal, antiviral, or antibiotic drugs (such as ketoconazole, ritonavir, clarithromycin, or nefazodone).
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When combining ACE inhibitors and ARBs together.
Drug Interactions
Tell your doctor about all medications you are taking, especially:
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Potassium-sparing diuretics or potassium supplements.
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ACE inhibitors or ARBs.
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Lithium.
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Cyclosporine or tacrolimus.
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NSAIDs (e.g., ibuprofen).
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Certain antibiotics and antifungals (ketoconazole, itraconazole, clarithromycin, telithromycin).
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St. John’s Wort, rifampicin, carbamazepine, phenytoin.
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Drugs that lower blood pressure (such as prazosin, amitriptyline, baclofen), as they may increase dizziness upon standing.
Storage
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Keep out of reach of children.
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Store at room temperature; no special storage conditions required.
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Do not use after the expiry date printed on the package.
Ingredients
Active ingredient:
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Eplerenone 50 mg per tablet.
Inactive ingredients:
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Lactose monohydrate
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Microcrystalline cellulose (E460)
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Croscarmellose sodium
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Hypromellose
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Sodium lauryl sulfate
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Talc (E553b)
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Magnesium stearate
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Titanium dioxide (E171)
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Macrogol (E1521)
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Polysorbate 80 (E433)
1-How long will it take for my order to be shipped?
Shipping takes 24 hours within Jeddah and Riyadh and two days for other regions
2-What is the return and exchange policy in the Al-Jawaher online store?
The customer has the right to request the return of an order within three days of receiving it; Provided that the product has not been used or opened and that the product is free of any defect or that the products are excluded from return or exchange
3-What products are not eligible for return or replacement?
**A: Products that require special storage conditions, such as refrigerated medications, milk, and baby food, are not eligible for return or replacement.
Deodorants and personal care and feminine hygiene products are not eligible for return or replacement unless the product is defective.**
4-How can I request a return or replacement?
Contact the number (+966 56 364 9160) on WhatsApp to request a return and exchange.
In the event of a return request: After confirmation, a return bill of lading will be issued and sent to the customer so that he delivers it* to the shipping company with the products in their original condition.
After confirming receipt by the shipping company, the process of returning the amount* minus the shipping value will begin within 5-7 business days.
In the event of an exchange request, a new shipping value will be calculated for the new order.
5-What happens if the product arrives damaged or incorrect?
In the event that the wrong product arrives from the shipping company (except for refrigerator medicines, milk, and baby food) or the wrong product arrives from Al-Jawaher Al-Mumayaz Pharmacy, please contact customer service, and after confirming the problem, the amount will be returned to the customer after the product is delivered to the shipping company.
If the problem is confirmed, we will bear the cost of sending the product to the shipping company’s branch via delivery applications, up to a maximum of 20 riyals, if it is confirmed that the shipping company’s branch is very far away.
6-What happens if the product arrives opened or used?
If the product arrives opened or used, the return request will be denied.
7-What happens if the customer does not receive the order from the shipping company and the product is returned to the shop?
If the customer does not receive the order from the shipping company and the product is returned to the shop, the shop will refund the customer's money, minus the shipping cost.
If the customer wants to re-ship the order, they will need to pay the shipping cost again.**
